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KMID : 0980720130320020196
Keimyung Medical Journal
2013 Volume.32 No. 2 p.196 ~ p.199
A Case of Anti-HAV IgM Positive in a Patient with Systemic Lupus Erythematosus
Song Seung Taek

Yoo In-Seol
Choi Jae-Woo
Kim Young
Park Chan-Keol
Kang Seong-Wook
Abstract
Many studies have been reported on the complex association between viruses and systemic lupus erythematosus (SLE), including hypotheses concerning the induction of SLE by viral infections through molecular mimicry, epitope spreading, activation of T cells by microbial superantigens, bystander activation, and activation of lymphocytes by lymphotropic viruses. During the past decade, many viruses have been brought up in the pathogenesis of SLE. However, HAV has not yet been mentioned as the etiology of SLE. Here, we report a patient tested anti-HAV IgM positive without clinical symptoms of acute hepatitis when diagnosed with new-onset SLE. Because SLE is an immune system disorder, we should take into consideration a variety of etiologies in diagnosis.
KEYWORD
Anti-HAV IgM, Hepatitis A virus, Systemic lupus erythematosus
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